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1

Chloride channels in cancer: Focus on chloride intracellular channel 1 and 4 (CLIC1 AND CLIC4) proteins in tumor development and as novel therapeutic targets

Peretti, Marta, Angelini, Marina, Savalli, Nicoletta, Florio, Tullio, Yuspa, Stuart H., Mazzanti, Michele

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2014

Language:

english

File:

PDF, 1.26 MB

english, 2014

2

Patient-derived xenograft in zebrafish embryos: a new platform for translational research in neuroendocrine tumors

Gaudenzi, Germano, Albertelli, Manuela, Dicitore, Alessandra, Würth, Roberto, Gatto, Federico, Barbieri, Federica, Cotelli, Franco, Florio, Tullio, Ferone, Diego, Persani, Luca, Vitale, Giovanni

Journal:

Endocrine (Springer)

Year:

2016

Language:

english

File:

PDF, 819 KB

english, 2016

3

Ruta graveolens L. Induces Death of Glioblastoma Cells and Neural Progenitors, but Not of Neurons, via ERK 1/2 and AKT Activation

Gentile, Maria Teresa, Ciniglia, Claudia, Reccia, Mafalda G., Volpicelli, Floriana, Gatti, Monica, Thellung, Stefano, Florio, Tullio, Melone, Mariarosa A. B., Colucci-D’Amato, Luca, Condorelli, Gerola

Journal:

Year:

2015

Language:

english

File:

PDF, 1.92 MB

english, 2015

4

Prion protein fragment 106–126 induces apoptotic cell death and impairment of L-type voltage-sensitive calcium channel activity in the GH3 cell line

Tullio Florio, Stefano Thellung, Carolina Amico, Mauro Robello, Mario Salmona, Orso Bugiani, Fabrizio Tagliavini, Gianluigi Forloni, Gennaro Schettini

Journal:

Journal of Neuroscience Research

Year:

1998

Language:

english

File:

PDF, 358 KB

english, 1998

5

Cultured astrocyte proliferation induced by extracellular guanosine involves endogenous adenosine and is raised by the co-presence of microglia

Renata Ciccarelli, Patrizia Di Iorio, Iolanda D'Alimonte, Patricia Giuliani, Tullio Florio, Francesco Caciagli, Pamela J. Middlemiss, Michel P. Rathbone

Journal:

Year:

2000

Language:

english

File:

PDF, 130 KB

english, 2000

6

Stereoselective Synthesis of Heterosubstituted Aziridines and Their Functionalization.

Luisella De Vitis, Saverio Florio, Catia Granito, Ludovico Ronzini, Luigino Troisi, Vito Capriati, Renzo Luisi, Tullio Pilati

Journal:

Year:

2004

File:

PDF, 91 KB

2004

7

ERK1/2 and p38 MAP kinases control prion protein fragment 90–231-induced astrocyte proliferation and microglia activation

Stefano Thellung, Valentina Villa, Alessandro Corsaro, Francesca Pellistri, Valentina Venezia, Claudio Russo, Antonio Aceto, Mauro Robello, Tullio Florio

Journal:

Year:

2007

Language:

english

File:

PDF, 516 KB

english, 2007

8

Inhibition of nuclear factor-κB activation induces apoptosis in cerebellar granule cells

Patrizia Piccioli, Carola Porcile, Sabrina Stanzione, Michela Bisaglia, Adriana Bajetto, Rudy Bonavia, Tullio Florio, Gennaro Schettini

Journal:

Journal of Neuroscience Research

Year:

2001

Language:

english

File:

PDF, 409 KB

english, 2001

9

Stereoselective synthesis of heterosubstituted aziridines and their functionalization

Luisella De Vitis, Saverio Florio, Catia Granito, Ludovico Ronzini, Luigino Troisi, Vito Capriati, Renzo Luisi, Tullio Pilati

Journal:

Year:

2004

Language:

english

File:

PDF, 434 KB

english, 2004

10

In vitro effect of human recombinant leptin and expression of leptin receptors on growth hormone-secreting human pituitary adenomas

Massimo Giusti, Liliana Bocca, Tullio Florio, Alessandro Corsaro, Renato Spaziante, Gennaro Schettini, Francesco Minuto

Journal:

Clinical Endocrinology

Year:

2002

Language:

english

File:

PDF, 1.11 MB

english, 2002

11

Characterization of the intracellular mechanisms mediating somatostatin and lanreotide inhibition of DNA synthesis and growth hormone release from dispersed human GH-secreting pituitary adenoma cells in vitro

Tullio Florio, Stefano Thellung, Alessandro Corsaro, Liliana Bocca, Sara Arena, Alessandra Pattarozzi, Valentina Villa, Alessandro Massa, Fabrizio Diana, Daria Schettini, Federica Barbieri, Jean Lou

Journal:

Clinical Endocrinology

Year:

2003

Language:

english

File:

PDF, 405 KB

english, 2003

12

β25–35 Alters Calcium Homeostasis and Induces Neurotoxicity in Cerebellar Granule Cells

Antonella Scorziello, Olimpia Meucci, Tullio Florio, Morena Fattore, Gianluigi Forloni, Mario Salmona, Gennaro Schettini

Journal:

Journal of Neurochemistry

Year:

1996

Language:

english

File:

PDF, 1.12 MB

english, 1996

13

Glial and Neuronal Cells Express Functional Chemokine Receptor CXCR4 and Its Natural Ligand Stromal Cell-Derived Factor 1

Adriana Bajetto, Rudy Bonavia, Simone Barbero, Patrizia Piccioli, Alfredo Costa, Tullio Florio, Gennaro Schettini

Journal:

Journal of Neurochemistry

Year:

1999

Language:

english

File:

PDF, 348 KB

english, 1999

14

Stromal cell-derived factor-1α induces astrocyte proliferation through the activation of extracellular signal-regulated kinases 1/2 pathway

Adriana Bajetto, Simone Barbero, Rudy Bonavia, Patrizia Piccioli, Paolo Pirani, Tullio Florio, Gennaro Schettini

Journal:

Journal of Neurochemistry

Year:

2001

Language:

english

File:

PDF, 571 KB

english, 2001

15

Contribution of two conserved glycine residues to fibrillogenesis of the 106–126 prion protein fragment. Evidence that a soluble variant of the 106–126 peptide is neurotoxic

Tullio Florio, Domenico Paludi, Valentina Villa, Daniela Rossi Principe, Alessandro Corsaro, Enrico Millo, Gianluca Damonte, Cristina D'Arrigo, Claudio Russo, Gennaro Schettini, Antonio Aceto

Journal:

Journal of Neurochemistry

Year:

2003

Language:

english

File:

PDF, 261 KB

english, 2003

16

Protective Effects of Some Creatine Derivatives in Brain Tissue Anoxia

Luisa Perasso, Gian Luigi Lunardi, Federica Risso, Anna V. Pohvozcheva, Maria V. Leko, Carlo Gandolfo, Tullio Florio, Aroldo Cupello, Sergey V. Burov, Maurizio Balestrino

Journal:

Neurochemical Research

Year:

2008

Language:

english

File:

PDF, 357 KB

english, 2008

17

In vivo and in vitro response to octreotide LAR in a TSH-secreting adenoma: characterization of somatostatin receptor expression and role of subtype 5

Federico Gatto, Federica Barbieri, Lara Castelletti, Marica Arvigo, Alessandra Pattarozzi, Francesca Annunziata, Alexandru Saveanu, Francesco Minuto, Lucio Castellan, Gianluigi Zona, Tullio Florio, Di

Journal:

Year:

2011

Language:

english

File:

PDF, 295 KB

english, 2011

18

Dual Modulation of ERK1/2 and p38 MAP Kinase Activities Induced by Minocycline Reverses the Neurotoxic Effects of the Prion Protein Fragment 90–231

Alessandro Corsaro, Stefano Thellung, Katia Chiovitti, Valentina Villa, Alessandro Simi, Federica Raggi, Domenico Paludi, Claudio Russo, Antonio Aceto, Tullio Florio

Journal:

Neurotoxicity Research

Year:

2009

Language:

english

File:

PDF, 579 KB

english, 2009

19

Modulation by GTP of Basal and Agonist-Stimulated Striatal Adenylate Cyclase Activity Following Chronic Blockade of D1 and D2 Dopamine Receptors: Involvement of G Proteins in the Development of Receptor Supersensitivity

Gennaro Schettini, Carmelo Ventra, Tullio Florio, Maurizio Grimaldi, Olimpia Meucci, Adriano Marino

Journal:

Journal of Neurochemistry

Year:

1992

Language:

english

File:

PDF, 851 KB

english, 1992

20

Different structural stability and toxicity of PrPARR and PrPARQ sheep prion protein variants

Domenico Paludi, Stefano Thellung, Katia Chiovitti, Alessandro Corsaro, Valentina Villa, Claudio Russo, Adriana Ianieri, Uwe Bertsch, Hans A. Kretzschmar, Antonio Aceto, Tullio Florio

Journal:

Journal of Neurochemistry

Year:

2007

Language:

english

File:

PDF, 291 KB

english, 2007

21

Expression of Chemokine Receptors in the Rat Brain

ADRIANA BAJETTO, RUDY BONAVIA, SIMONE BARBERO, TULLIO FLORIO, ALFREDO COSTA, GENNARO SCHETTINI

Journal:

Annals of the New York Academy of Sciences

Year:

1999

File:

PDF, 3.00 MB

1999

22

Expression of the Chemokine Receptor CXCR4 and Its Ligand Stromal Cell-Derived Factor 1 in Human Brain Tumors and Their Involvement in Glial Proliferation in Vitro

SIMONE BARBERO, ADRIANA BAJETTO, RUDY BONAVIA, CAROLA PORCILE, PATRIZIA PICCIOLI, PAOLO PIRANI, JEAN LOUIS RAVETTI, GIANLUIGI ZONA, RENATO SPAZIANTE, TULLIO FLORIO, GENNARO SCHETTINI

Journal:

Annals of the New York Academy of Sciences

Year:

2002

File:

PDF, 16.62 MB

2002

23

Proteasome Inhibitors Induce Cerebellar Granule Cell Death : Inhibition of Nuclear Factor-kB Activation

CAROLA PORCILE, PATRIZIA PICCIOLI, SABRINA STANZIONE, ADRIANA BAJETTO, RUDY BONAVIA, SIMONE BARBERO, TULLIO FLORIO, GENNARO SCHETTINIA

Journal:

Annals of the New York Academy of Sciences

Year:

2002

File:

PDF, 6.17 MB

2002

24

The rat tyrosine phosphatase η increases cell adhesion by activating c-Src through dephosphorylation of its inhibitory phosphotyrosine residue

Pera, Ilaria Le, Iuliano, Rodolfo, Florio, Tullio, Susini, Christiane, Trapasso, Francesco, Santoro, Massimo, Chiariotti, Lorenzo, Schettini, Gennaro, Viglietto, Giuseppe, Fusco, Alfredo

Journal:

Year:

2005

Language:

english

File:

PDF, 293 KB

english, 2005

25

Characterization of the Proapoptotic Intracellular Mechanisms Induced by a Toxic Conformer of the Recombinant Human Prion Protein Fragment 90–231

VALENTINA VILLA, ALESSANDRO CORSARO, STEFANO THELLUNG, DOMENICO PALUDI, KATIA CHIOVITTI, VALENTINA VENEZIA, MARIO NIZZARI, CLAUDIO RUSSO, GENNARO SCHETTINI, ANTONIO ACETO, TULLIO FLORIO

Journal:

Annals of the New York Academy of Sciences

Year:

2006

Language:

english

File:

PDF, 194 KB

english, 2006

26

Amyloid Precursor Protein Modulates ERK-1 and -2 Signaling

VALENTINA VENEZIA, MARIO NIZZARI, EMANUELA REPETTO, ELISABETTA VIOLANI, ALESSANDRO CORSARO, STEFANO THELLUNG, VALENTINA VILLA, PIA CARLO, GENNARO SCHETTINI, TULLIO FLORIO, CLAUDIO RUSSO

Journal:

Annals of the New York Academy of Sciences

Year:

2006

Language:

english

File:

PDF, 116 KB

english, 2006

27

Amino-Terminally Truncated Prion Protein PrP90-231 Induces Microglial Activation in Vitro

STEFANO THELLUNG, ALESSANDRO CORSARO, VALENTINA VILLA, VALENTINA VENEZIA, MARIO NIZZARI, MICHELA BISAGLIA, CLAUDIO RUSSO, GENNARO SCHETTINI, ANTONIO ACETO, TULLIO FLORIO

Journal:

Annals of the New York Academy of Sciences

Year:

2007

Language:

english

File:

PDF, 148 KB

english, 2007

28

Amyloid Precursor Protein and Presenilin 1 Interaction Studied by FRET in Human H4 Cells

MARIO NIZZARI, VALENTINA VENEZIA, PAOLO BIANCHINI, VALENTINA CAORSI, ALBERTO DIASPRO, EMANUELA REPETTO, STEFANO THELLUNG, ALESSANDRO CORSARO, PIA CARLO, GENNARO SCHETTINI, TULLIO FLORIO, CLAUDIO RUSSO

Journal:

Annals of the New York Academy of Sciences

Year:

2007

Language:

english

File:

PDF, 99 KB

english, 2007

29

Molecular mechanisms of the antiproliferative activity of somatostatin receptors (SSTRs) in neuroendocrine tumors

Journal:

Frontiers in Bioscience

Year:

2008

Language:

english

File:

PDF, 478 KB

english, 2008

30

Chemokines and Their Receptors in the Central Nervous System

Adriana Bajetto, Rudy Bonavia, Simone Barbero, Tullio Florio, Gennaro Schettini

Journal:

Frontiers in Neuroendocrinology

Year:

2001

Language:

english

File:

PDF, 327 KB

english, 2001

31

NDM29, a RNA polymerase III-dependent non coding RNA, promotes amyloidogenic processing of APP and amyloid β secretion

Sara Massone, Eleonora Ciarlo, Serena Vella, Mario Nizzari, Tullio Florio, Claudio Russo, Ranieri Cancedda, Aldo Pagano

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2012

Language:

english

File:

PDF, 1.51 MB

english, 2012

32

Receptor tyrosine kinase inhibitors and cytotoxic drugs affect pleural mesothelioma cell proliferation: insight into EGFR and ERK1/2 as antitumor targets

Federica Barbieri, Roberto Würth, Roberto E. Favoni, Alessandra Pattarozzi, Monica Gatti, Alessandra Ratto, Angelo Ferrari, Adriana Bajetto, Tullio Florio

Journal:

Biochemical Pharmacology

Year:

2011

Language:

english

File:

PDF, 1.34 MB

english, 2011

33

Expression of CXCR7 chemokine receptor in human meningioma cells and in intratumoral microvasculature

Roberto Würth, Federica Barbieri, Adriana Bajetto, Alessandra Pattarozzi, Monica Gatti, Carola Porcile, Gianluigi Zona, Jean-Louis Ravetti, Renato Spaziante, Tullio Florio

Journal:

Journal of Neuroimmunology

Year:

2011

Language:

english

File:

PDF, 1.40 MB

english, 2011

34

17A, a novel non-coding RNA, regulates GABA B alternative splicing and signaling in response to inflammatory stimuli and in Alzheimer disease

Sara Massone, Irene Vassallo, Gloria Fiorino, Manuele Castelnuovo, Federica Barbieri, Roberta Borghi, Massimo Tabaton, Mauro Robello, Elena Gatta, Claudio Russo, Tullio Florio, Giorgio Dieci, Ranieri

Journal:

Neurobiology of Disease

Year:

2011

Language:

english

File:

PDF, 1.26 MB

english, 2011

35

Isolation of stem-like cells from spontaneous feline mammary carcinomas: Phenotypic characterization and tumorigenic potential

Federica Barbieri, Roberto Wurth, Alessandra Ratto, Chiara Campanella, Guendalina Vito, Stefano Thellung, Antonio Daga, Michele Cilli, Angelo Ferrari, Tullio Florio

Journal:

Experimental Cell Research

Year:

2012

Language:

english

File:

PDF, 2.08 MB

english, 2012

36

Intracellular Signalling Mediating HIV-1 gp120 Neurotoxicity

Antonella Scorziello, Tullio Florio, Adriana Bajetto, Gennaro Schettini

Journal:

Cellular Signalling

Year:

1998

Language:

english

File:

PDF, 209 KB

english, 1998

37

Somatostatin receptor 1 (SSTR1)-mediated inhibition of cell proliferation correlates with the activation of the MAP kinase cascade: role of the phosphotyrosine phosphatase SHP-2

Tullio Florio, Stefano Thellung, Sara Arena, Alessandro Corsaro, Adriana Bajetto, Gennaro Schettini, Philip J.S. Stork

Journal:

Journal of Physiology-Paris

Year:

2000

Language:

english

File:

PDF, 157 KB

english, 2000

38

Goat anti-human GM-CSF recognizes canine GM-CSF

Alessandra Ratto, Claudio Petterino, Tullio Florio, Federica Barbieri

Journal:

Veterinary Clinical Pathology

Year:

2012

Language:

english

File:

PDF, 132 KB

english, 2012

39

Preclinical studies identify novel targeted pharmacological strategies for treatment of human malignant pleural mesothelioma

Roberto E Favoni, Antonio Daga, Paolo Malatesta, Tullio Florio

Journal:

British Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 2.61 MB

english, 2012

40

Intracellular Calcium Rise through L-Type Calcium Channels, as Molecular Mechanism for Prion Protein Fragment 106-126-Induced Astroglial Proliferation

Tullio Florio, Maurizio Grimaldi, Antonella Scorziello, Mario Salmona, Orso Bugiani, Fabrizio Tagliavini, Gianluigi Forloni, Gennaro Schettini

Journal:

Biochemical and Biophysical Research Communications

Year:

1996

Language:

english

File:

PDF, 407 KB

english, 1996

41

Apoptotic Cell Death and Impairment of L-Type Voltage-Sensitive Calcium Channel Activity in Rat Cerebellar Granule Cells Treated with the Prion Protein Fragment 106–126

Stefano Thellung, Tullio Florio, Valentina Villa, Alessandro Corsaro, Sara Arena, Carolina Amico, Mauro Robello, Mario Salmona, Gianluigi Forloni, Orso Bugiani, Fabrizio Tagliavini, Gennaro Schettini

Journal:

Neurobiology of Disease

Year:

2000

Language:

english

File:

PDF, 281 KB

english, 2000

42

p38 MAP Kinase Mediates the Cell Death Induced by PrP106–126 in the SH-SY5Y Neuroblastoma Cells

Stefano Thellung, Valentina Villa, Alessandro Corsaro, Sara Arena, Enrico Millo, Gianluca Damonte, Umberto Benatti, Fabrizio Tagliavini, Tullio Florio, Gennaro Schettini

Journal:

Neurobiology of Disease

Year:

2002

Language:

english

File:

PDF, 343 KB

english, 2002

43

Interleukin 1 beta inhibition of TRH-stimulated prolactin secretion and phosphoinositides metabolism

Gennaro Schettini, Elisa Landolfi, Maurizio Grimaldi, Olimpia Meucci, Alfredo Postiglione, Tullio Florio, Carmelo Ventra

Journal:

Biochemical and Biophysical Research Communications

Year:

1989

Language:

english

File:

PDF, 569 KB

english, 1989

44

Somatostatin inhibition of anterior pituitary adenylate cyclase activity: different sensitivity between male and female rats

Gennaro Schettini, Tullio Florio, Olimpia Meucci, Elisa Landolfi, Gaetano Lombardi, Adriano Marino

Journal:

Year:

1988

Language:

english

File:

PDF, 744 KB

english, 1988

45

Somatostatin inhibition of adenylate cyclase activity in different brain areas

Gennaro Schettini, Tullio Florio, Olimpia Meucci, Elisa Landolfi, Maurizo Grimaldi, Carmelo Ventra, Adriano Marino

Journal:

Year:

1989

Language:

english

File:

PDF, 552 KB

english, 1989

46

Age-related alterations of somatostatin gene expression in different rat brain areas

Tullio Florio, Carmelo Ventra, Alfredo Postiglione, Gennaro Schettini

Journal:

Year:

1991

Language:

english

File:

PDF, 590 KB

english, 1991

47

Somatostatin and SMS 201-995 reverse the impairment of cognitive functions induced by cysteamine depletion of brain somatostatin

Gennaro Schettini, Tullio Florio, Gianludovico Magri, Maurizio Grimaldi, Olimpia Meucci, Elisa Landolfi, Adriano Marino

Journal:

European Journal of Pharmacology

Year:

1988

Language:

english

File:

PDF, 763 KB

english, 1988

48

High hydrophobic amino acid exposure is responsible of the neurotoxic effects induced by E200K or D202N disease-related mutations of the human prion protein

Alessandro Corsaro, Stefano Thellung, Tonino Bucciarelli, Luca Scotti, Katia Chiovitti, Valentina Villa, Cristina D’Arrigo, Antonio Aceto, Tullio Florio

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2011

Language:

english

File:

PDF, 1.12 MB

english, 2011

49

The pathological prion protein forms ionic conductance in lipid bilayer

Daniele Paulis, Bruno Maras, M. Eugenia Schininà, Laura di Francesco, Serena Principe, Roberta Galeno, Hanin Abdel-Haq, Franco Cardone, Tullio Florio, Maurizio Pocchiari, Michele Mazzanti

Journal:

Neurochemistry International

Year:

2011

Language:

english

File:

PDF, 712 KB

english, 2011

50

Persistent increase of d-aspartate in d-aspartate oxidase mutant mice induces a precocious hippocampal age-dependent synaptic plasticity and spatial memory decay

Francesco Errico, Robert Nisticò, Francesco Napolitano, Alessandra Bonito Oliva, Rosaria Romano, Federica Barbieri, Tullio Florio, Claudio Russo, Nicola B. Mercuri, Alessandro Usiello

Journal:

Neurobiology of Aging

Year:

2011

Language:

english

File:

PDF, 2.28 MB

english, 2011